Maurice C. video

Identity and charge heterogeneity

Streamline your CE workflow with Maurice C who delivers identity, purity and heterogeneity data on your biologics fast. This cIEF application video show how you can get reliable data in 10 minutes.

Meet Maurice: cIEF Application

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About Maurice and Electrophoresis

Meet Maurice. The advanced capillary electrophoresis (CE) platform. He's a real problem solver.

Switch between the capillary isoelectric focusing (cIEF) and capillary electrophoresis sodium dodecyl sulfate (CE-SDS) easily and quickly.

Get identity, purity, and heterogeneity data on your biologics. Maurice helps you develop platform methods fast, so you can get to robust results even faster.

Your cIEF and CE-SDS methods are developed in a day. This plug-and-play system uses dedicated and integrated cartridges for each application.

Streamlining your application workflow, preventing cross-contamination, ensuring low reagent usage, and managing waste.

The simple workflow from setup to data analysis reduces variability.

CE-SDS Workflows With Maurice

Let's get started with purity and heterogeneity analysis of your monoclonal antibody with CE-SDS.

Simply place the running buffer vial inside the CE-SDS cartridge and insert into Maurice. Load the reagents and your samples, close the door, setup a batch, and press start.

Maurice will do the rest for you. The sample is injected into the cartridge based on the location you defined in the batch.

Compass software for iCE lets you run multiple methods in the same batch, monitors the separations in real-time, and automatically analyzes the data for you.

Maurice and Data Analysis

With Maurice, you can analyze molecules in a wide molecular weight range.

With this streamlined workflow, you get reproducible results in under 35 minutes - helping you to get your purity and heterogeneity data faster.

cIEF and Maurice

Let's get started with identity and heterogeneity analysis of your biologics with cIEF.

Simply add electrolytes into the tanks of your cartridge and insert into Maurice. Load your samples and reagents, then close the door. Set up the batch and press Start. Maurice will do the rest for you.

The sample is injected into the cartridge based on location you define in the batch. The whole column imaging with cIEF allows you to monitor the separation in real-time.

Maurice collects data in both absorbance and fluorescence modes simultaneously for each injection. Compass software for iCE then automatically analyzes the data for you.

With this simple and streamlined workflow, wide pI range for separation, and highly reproducible data across the entire life of the cartridge, you can generate platform methods within a day, and get results in just 6-10 minutes.

Fluorescence Versus Absorbance

Native fluorescence mode delivers higher sensitivity compared to absorbance mode. Don't get tied down in capillaries or bogged down with lengthy and messy cleanups.

Partner with Maurice to develop methods fast, complete analysis quickly and generate data you can trust. Data to move forward. You can focus on science. With Maurice, win the race to FDA submission.

Learn more about Maurice by ProteinSimple, a Bio-Techne brand, by visiting the Maurice instrument page.

MAURICE’S TECHNOLOGY

Gold-standard iCE technology is at the heart of Maurice. Translation? You get crazy reliable and reproducible data day in and day out with single-digit CVs. We also added native fluorescence detection to give you higher sensitivity with quieter baselines. In this short video, we highlight the key benefits of the new platform for CE analysts. Find out how Maurice makes CE easy with his streamlined workflow and delivers identity, purity and heterogeneity data on your biologics fast.

CAPILLARY ISOELECTRIC FOCUSING (CIEF) AND MAURICE

Maurice conducts identity and heterogeneity analysis of your biologics with capillary isoelectric focusing (cIEF). It works as simply as adding electrolytes into the tanks of your cartridge. Insert the cartridge into Maurice, load your samples and reagents, and close the door. Once the batch is setup to run, press “Start”. Maurice beings its run and takes care of the rest.

As a Maurice user, you can define the batches’ sample injections into the cartridge. Separation monitoring allows you to view results as they happen with the whole column imaging with cIEF. Maurice’s dual absorbance and fluorescence modes enables simultaneous data collection for each injection while the Compass software for iCE analyzes the data for you automatically.

User defined capillary isoelectric focusing (cIEF) sample injection into Maurice’s cartridge during a batch run.

GETTING MORE RESULTS WITH MAURICE

Maurice allows you to generate platform methods in a day and get results in 6 to 10 minutes. This is all made possible with the streamlined workflow, wide pI range for separation, and highly reproducible data across the cartridge’s entire life.

COMPARING MODES: FLUORESCENCE AND ABSORBANCE

The native fluorescence mode delivers higher sensitivity when compared to absorbance mode on Maurice. Do not let capillaries tie you down as well as long and arduous cleanup processes. Optimize your workflows with Maurice.

If you need to develop methods quickly, Maurice is the go-to instrument. He completes analysis quickly with cIEF and generates high-quality, trustworthy data.