Ella HCP Assay
Fast, Reproducible, Automated Host Cell Protein Measurement with Simple Plex
Host-cell proteins (HCP) are proteins produced or translated by the host organism during recombinant therapeutic proteins or biologics production. An important requirement during production is to reduce the amount of HCPs at every phase of the purification process since they complicate the efficacy of the biologic, causing immunogenicity as well an immune response when administered to a patient.
ProteinSimple, a Bio-Techne brand, has a Simple Plex™ HCP assay that runs on Ella™, an automated immunoassay system. Simple Plex assays offer better precision, greater dynamic range at 4-5 logs, gives you results in just 1 hour. Ella also eliminates all the manual steps that lead to poor data quality and inconsistent results. Factory calibrated standard curves that come with each cartridge make it unneccessary to prepare your own standard curve in non-GMP settings, saving you significant time and cost.
Simple Plex HCP Assay
Our HCP assays are customized to your specific HCP needs. Just send us your HCP capture and detection antibodies and HCP standards. We'll create and design your HCP Simple Plex assay for use on the Ella Instrument. The HCP assay will be formatted using the 72 x 1 cartridge which allows up to 72 individual samples to be run on a single cartridge. The procedure for processing the HCP cartridge is simple. Pipette your samples onto the cartridge, press Start in the Ella software Explorer, and the samples will be automatically processed, read, and analyzed in 1 hour. To get started, please fill out the HCP Assay Request form (link below).
|HCP Simple Plex Assay||Ten 72 x 1 cartridges for the detection of HCP for use on the Ella Instrument—User to supply antibodies||SPCKB-ASSAYDEV||Use HCP Assay Request form
1. Cho Host Cell Proteins 3rd Generation, CYGNUS Product Insert (2015).